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系統識別號 U0007-1704200715031610
論文名稱(中文) 影響肺癌病人疲憊、憂鬱與睡眠品質之相關因素探討
論文名稱(英文) Fatigue, Depression, and Sleep Quality in Patients With Lung Cancer
校院名稱 臺北醫學大學
系所名稱(中) 護理學研究所
系所名稱(英) Graduate Institute of Nursing
學年度 94
學期 2
出版年 95
研究生(中文) 姚如玲
研究生(英文) Ju-Ling Yao
學號 G455091005
學位類別 碩士
語文別 中文
口試日期
論文頁數 145頁
口試委員 指導教授-林佳靜
中文關鍵字 疲憊  憂鬱  睡眠品質 
英文關鍵字 fatigue  depression  sleep quality 
學科別分類
中文摘要 本研究目的主要探討肺癌病人之疲憊、憂鬱與睡眠品質情形、影響之相關因素、其彼此間相關性及其預測因素。研究對象來源為北部一所醫學中心及一所區域教學醫院之胸腔內科及腫瘤科病房,以立意取樣方式收集147位肺癌病人,採用相關性及橫斷式之研究設計,研究工具包括「基本資料問卷」、「台灣版簡明疲憊量表」、「醫院焦慮憂鬱量表」、「匹茲堡睡眠品質量表」等四部分,資料分析包括描述性統計分析、t-test、單因子變異數分析、皮爾森相關、多元迴歸分析等。 研究結果發現:(1)肺癌病人疲憊嚴重程度方面,平均值為5.85分,屬於中度;憂鬱情形方面,平均值為9.87分,為疑似憂鬱情形;睡眠品質方面,平均分數為10.86分,屬於睡眠品質不良情形。(2)性別、職業與疲憊嚴重程度在統計學上有顯著差異,婚姻狀況、宗教信仰、居住情形、主要照顧者、年齡、教育年資方面與疲憊之間,則無顯著差異存在;有無職業與憂鬱程度有統計學上顯著差異,性別、婚姻狀況、宗教信仰、居住情形、主要照顧者、年齡、教育年資方面與憂鬱之間,則無顯著差異;性別、職業、主要照顧者方面與睡眠品質在統計學上有顯著差異存在,婚姻狀況、宗教信仰、居住情形、年齡、教育年資方面與睡眠品質之間則無差異存在。(3)KPS分數、肺癌症狀指標(Pain, Dyspnea, Cough)與疲憊、憂鬱、睡眠品質三者個別之關係,結果皆呈現顯著負相關。腫瘤形態、是否轉移、是否程接受手術及治療方式與疲憊、憂鬱、睡眠品 質三者個別之間,在統計學上無顯著差異存在;罹病時間及三頭肌皮層厚度與疲憊、憂鬱、睡眠品質三者個別之間,無顯著相關。而Albumin值與疲憊、憂鬱之間,在統計學上無顯著差異存在,但與睡眠品質之間則呈現顯著負相關(r=- .293, p< .05)。(4)肺癌病人疲憊嚴重程度、憂鬱情形與睡眠品質三者彼此之間呈現顯著正相關。性別、KPS分數及憂鬱嚴重程度等為疲憊之重要預測因子;KPS分數、疲憊程度及睡眠品質為憂鬱的重要預測因子;憂鬱嚴重程度為睡眠品質之重要預測因子。 由研究結果得知,疲憊、憂鬱與睡眠品質不良情形,為大多數肺癌病人皆有之問題,並多達中等以上之嚴重程度。期藉由本研究發現,能提供臨床醫護人員對於肺癌病人有更多的瞭解,使肺癌病人在照護品質上更臻完美。
英文摘要 The purpose of this study is to explore the related factors, correlations, and predictors of fatigue, depression, and sleep quality in patients with lung cancer. The research subjects originate from the chest medicine department and oncology ward of a medical center and a regional teaching hospital in the North. Purposive sampling was used to collect 147 lung cancer patients who were evaluated according to research design of descriptive correlational and cross-sectional design. Research instruments included “Brief Fatigue Inventory-Taiwan form,” “Hospital Anxiety and Depression Scale,” “Pittsburgh Sleep Quality index.”The data are analyzed by descriptive statistical analysis, t-test, one-way ANOVA, Pearson’s correlation, and multiple regression.The findings are as follows: 1. The seriousness of fatigue in lung cancer patients had a mean value of 5.85 points, the degree of fatigue was medium. As for depression, the mean value was 9.87 points, constituting a state in which depression was suspected. Regarding sleep quality, the mean score was 10.86 points, in the category of poor sleep quality. 2. Gender, occupation, and seriousness of fatigue showed a significant statistical difference, but there was no significant statistical difference between fatigue and marital status, religion, residency, main caregiver, age, and years in education. Gender, occupation, main caregiver showed a significant statistical difference with respect to quality of sleep, but there was no significant statistical difference between sleep quality and marital status, religion, residency, age, and years in education. 3. KPS score, the lung cancer symptom scale (pain, dyspnea, and cough) had a significantly negative correlation with fatigue, depression, as well as sleep quality. Cancer type, whether metastatsis, occurred, whether the patient had underwent an operation, and treatment method did not show a statistically significant different with respect to fatigue, depression, and sleep quality. The time of suffering from the illness and skin fold did not show a significant correlation to fatigue, depression, and sleep quality. Albumin value did not have a significant statistical difference with respect to fatigue and depression, but it had a negative correlation to sleep quality. 4. Fatigue seriousness, depression, and sleep quality in cancer patients showed a positive correlation. Gender, KPS score, and seriousness of depression were important predictive factors for fatigue. KPS score, fatigue seriousness, and sleep quality were important predictive factors for depression. The seriousness of depression was an important predictive factor for sleep quality. The research results showed that the majority of lung cancer patients had the problems of fatigue, depression, and poor sleep quality, many of whom had at least a seriousness level of medium. The results of the study provide more understanding and greater care quality of lung cancer patients.
論文目次 目錄 致 謝………………………………………………………………..…Ⅰ 中文摘要……………………………………………………………..……Ⅲ 英文摘要…………………………………………………………………..Ⅴ 目 錄……………………………………………………………..……Ⅶ 圖表目次……………………………………………….………………….Ⅹ 第一章 緒論 第一節 研究動機……………………………………………………1 第二節 研究重要性…………………………………………………3 第三節 研究目的……………………………………………………5 第二章 文獻查證 第一節 肺癌…………………………………………………………..6 第二節 癌症疲憊之相關研究…………………………...………….10 第三節 癌症憂鬱之相關研究……………………...……………….15 第四節 癌症睡眠品質之相關研究……………………….…..…….20 第五節 疲憊、憂鬱與睡眠品質之相關性研究………………...….22 第三章 研究方法 第一節 研究架構……………………………………………………25 第二節 研究假設……………………………………………………27 第三節 名詞解釋……………………………………………………28 第四節 研究設計……………………………………………………29 第五節 研究場所及對象……………………………………………30 第六節 研究工具……………………………………………………31 第七節 資料收集過程……………………………………….……...38 第八節 資料分析…………………………………………….……...39 第四章 分析與結果 第一節 研究對象之基本屬性及疾病特性…………………...…….41 第二節 肺癌病人疲憊、憂鬱及睡眠品質之程度………..…..……50 第三節 肺癌病人疲憊、憂鬱、睡眠品質與基本屬性及疾病特性 之相關…………………………………..………………..…59 第四節 肺癌病人疲憊、憂鬱與睡眠品質之相關性………..……..71 第五節 肺癌病人疲憊、憂鬱與睡眠品質之預測因子………..…..73 第五章 討論 第一節 肺癌病人之疲憊、憂鬱與睡眠品質之程度………….…...79 第二節 肺癌病人之疲憊、憂鬱、睡眠品質與基本屬性之相關....83 第三節 肺癌病人之疲憊、憂鬱、睡眠品質與疾病特性及治療相 關………..……………………………………………..……90 第四節 肺癌病人之疲憊、憂鬱、睡眠品質之相關性………..…..97 第五節 肺癌病人之疲憊、憂鬱、睡眠品質之預測因子……..….101 第六章 結論與建議 第一節 結論…………………………………………………………108 第二節 研究限制………………………………………….…….…..113 第三節 建議……………………………………………………..…..115 參考資料 中文部分…………………………………………………………..…117 英文部分…………………………………………………………..…121 研究附錄 附錄一 研究同意書……………………………………………..…132 附錄二 個人基本資料…………………………………………..…133 附錄三 台灣版簡明疲憊量表…………………………………..…134 附錄四 醫院焦慮憂鬱量表……………………………………..…135 附錄五 匹茲堡睡眠品質指標………………………………..…....138 附錄六 匹茲堡睡眠品質計分標準……………………………..…140 附錄七 Karnofsky 功能狀態量表……………………………..….141 附錄八 肺癌症狀指標…………………………………………..…142 附錄九 醫院焦慮憂鬱量表使用授權書………………………..…143 圖表目次 圖一 研究架構……………………………………………………..….….26 表一 量表信度測試結果………………………………….….……..……37 表二 資料處理及分析方法………………………………….………..….40 表三 肺癌病人之個人基本屬性分佈情形…………………………..…..43 表四 肺癌病人疾病特性及治療分佈情形………………….……..…….48 表五 肺癌病人疲憊、憂鬱及睡眠品質分佈情形…………..………….55 表六 肺癌病人匹茲堡睡眠品質指標量表(PSQI)七個構成要素得 分情形…………………………………………………….…….….56 表七 肺癌病人匹茲堡睡眠品質指標量表(PSQI)各分項分佈情形...57 表八 肺癌病人睡眠困擾發生情形………………………………….…..58 表九 肺癌病人個人基本屬性與疲憊、憂鬱、睡眠品質之相關性..….61 表十 肺癌病人疾病特性及治療與疲憊、憂鬱、睡眠品質之相關..….68 表十一 疲憊嚴重程度、憂鬱程度與PSQI睡眠品質總分之相關表….72 表十二 肺癌病人疲憊之預測因素……………………………….……...74 表十三 肺癌病人憂鬱之預測因素…………………………………...….76 表十四 肺癌病人睡眠品質之預測因素…………………………..….….78
參考文獻 參考文獻 中文部分 王文娟(2004)?頭頸癌患者症狀嚴重度、情緒狀態與睡眠品質之探討?未發表的碩士論文,國立台北護理學院,台北。 王令瑋(1995)?小細胞肺癌的放射線治療?臨床醫學,35(3),167-177。 王潤清(2004)?慢性疼痛對情緒狀態、睡眠品質之影響:慢性癌痛與慢性每日頭痛之比較?未發表的碩士論文,臺北醫學大學,台北。 白玉珠、鄒怡真、黃鈴雅、雍海鵬(2001)?肺癌患者生活品質及其相關因素之研究?腫瘤護理雜誌,1(1),1-17。 行政院衛生署(2001,12月30日)?台灣地區主要死亡原因統計表?衛生署衛生統計資訊網首頁?取自1月20日,2003,http://www.doh.gov.tw/newverprog/proclaim/content。 李芸湘、蔡芸芳、賴裕和、高瑞和(2002)?肺癌病人在化學治療期間疲憊程度及其相關因素?台灣醫學,6(6),797-804。 李明濱(1985)?癌症住院病人之精神疾病-135例照會個案及對照組之比較研究?台灣醫誌,1,98-110。 吳佳儀(2002)?社區老人睡眠品質與身體活動、憂鬱之相關性探討?未發表的碩士論文,國立台灣大學,台北。 邱昭華(2002a)?小細胞肺癌之診斷、治療及追蹤?取自10月11日,2002,http://www.vghtpe.gov.tw/~tcfund/blood/blood_2.htm。 邱昭華(2002b)?非小細胞肺癌之診斷、治療及追蹤?取自10月18日,2002,http://www.vghtpe.gov.tw/~tcfund/blood/blood_3.htm。 林玲華、陳景彥、劉嘉逸、陳美伶(2002)?癌症住院病人憂鬱狀態的盛行率及預測因素?台灣醫學,6(4),535-545。 林嘉玲、蘇東平、張媚(2003)?機構老人之睡眠品質及其相關因素?台灣醫學,7(2),174-184。 封威蓮(2003)?住院癌症病人營養狀況之探討?未發表的碩士論文,臺北醫學大學,台北。 施議強、侯承伯、馬景野(2000)?失眠的評估與治療?基層醫學,16(1),2-8。 徐長庚、曾國華、陳榮基(1999)?失眠的原因與藥物治療?基層醫學,15(8),168-174。 唐秀治(1993)?癌症治療的另一章-癌症病人之心理支持?護理新象,3 (10),446-451 。 黃士懿(2002)?重鬱症患者紅血球細胞膜磷脂質及血漿脂肪酸組成之分析?未發表的碩士論文,臺北醫學大學,台北。 商志雍、李明濱、廖士程(2002)?癌症病人常見之精神疾病?台北市醫師公會會刊,46(2),15-19。 許秀如(1991)?癌症患者的心理及其護理?榮總護理,8(4),446-450。 張玉珠(1995)?肺癌病人接受放射線治療期間疲憊程度及其相關因素的探討?未發表的碩士論文,國防醫學院,台北。 張青蕙(2002)?住院癌症病患疲憊問題及其相關因素之探討?未發表的碩士論文,臺北醫學大學,台北。 張愛萍(2002)?發展台灣版簡明疲憊量表與台灣版安德森症狀量表及信效度檢測?未發表的碩士論文,臺北醫學大學,台北。 張議文(2001)?癌症相關的疲勞?台灣醫學,5(6),714-718。 陳佩英、史麗珠、王正旭、賴裕和、張獻崑、陳美伶(1999)?疼痛對癌症病人焦慮與憂鬱之影響?台灣醫學,3(4),373-381。 國家衛生研究院(1998)?肺癌診治共識?取自8月11日,1998, http://www.nhri.org.tw/nhri_org/ca/doc/main2_1_4.doc。 曾光毅、許宗達、羅中廷、李冠錦、洪淑華、許清吉、曾嵩智(2002)?現階段肺癌的預防與治療?基層醫學,17(10),210-216。 趙美珍(2004)?肝硬化病患疲倦與睡眠品質之相關因素探討?未發表的碩士論文,臺北醫學大學,台北。 廖士程、李明濱(2001)?癌症病人之身心問題?台灣醫學,5(4),433-439。 劉桂芬(1999)?肺癌病患症狀困擾與功能狀態之相關性探討?未發表的碩士論文,國立陽明大學,台北。 潘雪幸(2004)?肺癌病患症狀盛行率嚴重度日常生活活動干擾及其相關因素探討?未發表的碩士論文,國防醫學院,台北。 鍾孟樺(2005)?台灣肝癌患者之症狀群集現象?未發表的碩士論文,台北醫學大學,台北。 蕭雅莉、賴裕和、邱仲峰、蔡若婷、葉啟源、鍾道生、高仲瑜、林美良 (2003)?肝癌患者接受立體定位放射線治療期間疲憊及血液數值變化之探討.放射治療與腫瘤學,10(4),197-208。 英文部分 Ahlberg, K., Ekman, T., Johansson, F., & Mock, V. (2003). Assessment and management of cancer-related fatigue in adults. The Lancet, 362(9384), 640. Aistars, J. (1987). Fatigue in the cancer patient:A conceptual approach to a clinical problem. Oncology Nursing Forum, 14 (6), 25-30. Akechi, T., Nakano, T. Okamura, H., et al. (2001). Psychiatric disorders in cancer patients: descriptive analysis of 1721 psychiatric referrals at two Japanese cancer hospitals. Japanese Journal of Clinical Oncology, 31(5), 188-194. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders(4th ed., rev.).Washington, DC: Author. Ancoli-Israel, S., Moore, P. J., & Jones, V. (2001). The relationship between fatigue and sleep in cancer patients: a review. European Journal of Cancer Care, 10 (4), 245-255. Anderson, K. O., Getto, C. J., Mendoza, T. R., et al. (2003). Fatigue and sleep disturbance in patients with cancer, patients with clinical depression, and community-dwelling adult. Journal of Pain and Symptom Management, 25(4), 307-318. Barnes, E. A., & Bruera, E. (2002). Fatigue in patients with advanced cancer:a review. International Journal of Gynecological Cancer, 12(5), 424-428. Beach, P., Siebeneck, B., Buderer, N. F., & Ferner, T. (2001). Relationship between fatigue and nutritional status in patients receiving radiation therapy to treat lung cancer. Oncology Nursing Forum, 28(6), 1027-1031. Berger, A. (2003). Treating fatigue in cancer patients. Oncologist, 8 (Supp1), 10-14. Berger, A. M., & Farr, L. (1999). The influence of daytime inactivity and nighttime restless on cancer-related fatigue. Oncology Nursing Forum, 26(10), 1663-1671. Berger, A. M., & Higginbotham, P. (2000). Correlates of fatigue during and following adjuvant breast cancer chemotherapy: a pilot study. Oncology Nursing Forum, 27(9), 1443-1448. Bottomley, A. (1998). Depression in cancer patients: a literature review. European Journal of Cancer Care, 7, 181-191. Breitbart, W. (1994). Pscholoncoogy: depression,anxiety,delirium. Semin Oncology, 121, 754-69. Brown, J. K., & Radke, K. J. (1998). Nutritional assessment, intervention, and evaluation of weight loss in patients with non-small cell lung cancer. Oncology Nursing Forum, 25(3), 547-553. Buccheri, G. (1998). Depressive reactions to lung cancer are common and often followd by a poor outcome. European Respiratory Journal, 11(1), 173-178. Buysse, D. J., Reynolds, C. F. D., Monk, T. H., et al. (1989). The Pittsburgh Sleep Quality Index: A new instrument for psychiatric practice and research. Psychiatry Research, 28(2), 193-213. Chang, H. K., & Chen, M. L.(2004). Physical symptom profiles of depressed and nondepressed patients with cancer. Palliative Medicine, 18(8), 712-718. Chen, M. L., Chang, H. K., & Yeh, C. H. (2000). Anxiety and depression in Taiwanese cancer patients with and without pain. Journal of Advanced Nursing, 32(4), 944-951. Chevalier, V., Mormont, M. C., Cure, H., & Chollet, P. (2003). Assessment of circadian rhythms by actimetry in healthy subjects and patients and patients with advanced colorectal cancer. Oncology Reports, 10(3), 733-737. Davidson, J. R., MacLean, A. W., Brundage, M. D., & Schulze, K. (2002). Sleep disturbance in cancer patients. Social Science & Medicine, 54 , 1309-1321. Derogatis, L. R., Morrow, G. R., Fetting, J.,et al. (1983). The prevalence of psychiatric disorders among cancer patients. Journal of the American Medical Association, 249, 751-7. Duncan, J. F., Donald, C. M., Robert, M. (2004). The correlation between fatigue, physical function, the systemic inflammatory response, and psychological distress in patients with advanced lung cancer. Cancer, 103 (2), 377-382. Engstrom, C. A., Htrohl, R. A., Rose, l., Lewandowski, l., &Stefanek, M. E. (1999). Sleep alterations in cancer patients. Cancer Nursing, 22 (2), 143-148. Everard, K., Aft, R., Schootman, M., Dietz, J., Herrmann, V., Hsueh, E.,et al. (2005). Associations among age, type of surgery, and psychosociall outcomes in women with in situ and early-stage breast cancer. The Gerontologist, 45(2), 11. Gelibter, A., Ceribelli, A., Pollera, C. F., Milella, M., Moscetti, L. Sperduti, I., & Cognetti, F. (2005). Impact of gefitinib (Iressa) treatment on the quality of life of patients with advanced non-small-cell lung cancer. Journal of Cancer Research and Clinical Oncology, 131 (12), 783-788. Gift , A. G., Jablonski, A., Stommel , M., & Given, C. W. (2004). Symptom clusters in elderly patients with lung cancer. Oncology Nursing Forum, 31(2), 202-212. Ginsburg, M. L., Quirt, C., Ginsburg, A. D., & Mackillop, W. J. (1995). Psychiatric illness and psychosocial concerns in patients with newly diagnosed lung cancer. Canadian Medical Association Journal, 152, 701-708. Hawson, G., Firouz-Abadi, A., Ford, C. A., Johnson, N. G., Zimmerman (1990). Primary lung cancer: characterisation and survival of 1024 patients treated in a single institution. Australian Journal of Medicine, 152, 230. Hickok, J. T., Morrow, G. R., McDonald, S., & Bellg, A. J. (1996). Frequency and correlates of fatigue in lung cancer patients receiving radiation therapy:implications for management. Journal of Pain and Symptom Management, 11(6), 370-377. Hollen, P. J., Gralla, R. J., Kris, M. G., Cox, C., Belani, C. P., Grunberg, S. M., et al. (1994). Measurement of quality of life in patients with lung cancer in multicenter trials of new therapies: psychometric assessment of the Lung Cancer Symptom Scale. Cancer, 73, 2087-2098. Hopwood, P., & Stephens, R. J. (2000). Depression in patients with lung cancer: prevalence and risk factors derived from quality-of-life data. Journal of Clinical Oncology , 18(4), 893-903. Iconomou, G., Mega, V., Koutras, A., Iconomou, A. V., & Kalofonos, H. P. (2004). Prospective assessment of emotional distress, cognitive function, and quality of life in patients with cancer treated with chemotherapy. Cancer, 101 (2), 404-411. Irvine, D.,Vincent, L.,Graydon, J. E., Bubela, N., & Thompson, L. (1994). The prevalence and correlates of fatigue in patients receiving treatment with chemotherapy and radiotherapy. Cancer Nursing, 17(5), 367-378. Jones, L. S. (1993). Correlates of fatigue and related outcomes in individuals with cancer undergoing treatment with chemotherapy. State University of New York at Buffalo. Koopman, C., Nouriani, B., Erickson, V., Anupindi, R., Bulter, L. D., Bachmann, M. H., et al. (2002). Sleep disturbances in women with metastatic breast cancer. Breast Journal, 8(6), 362-370. Levin, R. D., Daehler, M. A., Grutsch, J. F., Quiton , J., Lis, C, G., Peterson, D., et al. (2005). Circadian function in patients with advanced non-small-cell lung cancer. The British Journal of Cancer, 93(11), 1202-1208. Lovejoy, N. C., Tabor, D., Margherite, M., & Lillis, P. (2000). Cancer-related depression : part-I—neurologic alterations and cognitive-behavioral therapy. Oncology Nursing Forum, 27 (4), 667-680. McDaniel, J. S., Musselman, D. L., Porter, M. R. Reed, D. A., & Nemeroff, C. B. (1995). Depression in patients with cancer. Archives of General Psychiatry, 52, 89-99. Miaskowski, C., Dodd, M., & Lee, K. (2004). Symptom clusters: The new frontier in symptom management research. Journal of the National Cancer Institute Monographs, 30, 17-21. Miaskowski, C., & Lee, K. A. (1999). Pain, fatigue, and sleep disturbances in oncology outpatients receiving radiation therapy for bone metastasis: a pilot study. Journal of Pain and Symptom Management, 17(5), 320-332. Minna, J. D. (2001). Neoplasms of the Lung. In E. Braunwald, A. S. Fauci, D. L. Kasper, S. L. Hauser, D. L. Longo & J. L. Jameson (Eds.), Harrisons Principles of International Medicine(15th ed., pp. 562-570). New York: McGraw-Hll. Mock,V., Atkinson. A., Barsevick, A. et al. (2000). National comprehensive cancer network oncology practice guidelines for cancer-related fatigue. Oncology, 14, 151-161. Mormont, M. C., Waterhouse, J., Bleuzen, P. et al. (2000). Marked 24-h rest/activity rhythms are associated with better quality of life, better response, and longer survival in patients with metastatic colorectal cancer and good performance status. Clinical Cancer Research, 6, 3038-3045. Mormont, M. C., & Waterhouse, J. (2002). Contribution of the rest-activity circadian rhythm to quality of life in cancer patients. Chronobiology International, 19 (1), 313-323. Mountain, C. F. (1997). Revision in the international system for staging lung cancer. Chest, 111, 1710. Mystakidou, K., Tsilika, E., Parpa, E., Katsouda, E., Galanos, A., Vlahos, L. (2005). Assessment of anxiety and depression in advanced cancer patients and their relationship with quality of life. Quality of Life Research, 14 (8), 1825-1833. Nail, L. M., & Winnningham, M. L. (1993). Fatigue. IN S. L. Groenwald, M. H. Frogge, M. Goodman, & C. H. Yarbro (Eds.), Cancer Nursing: principles and practice (3rd ed., pp 608-619). Boston: Jones & Bartlett. Okamura, M., Yamawaki, S., Akechi, T., Taniguchi, K., & Uchitomi, Y. (2005). Psychiatric disorders following first breast cancer recurrence: prevalence, associated factors and relationship to quality of life. Japanese Journal of Clinical Oncology, 35(6), 302-309. Okuyama, T.,Tanaka, K., Akechi,T., Kugaya, A., Okamura, H., Nishiwaki, Y., & Uchitomi, Y. (2001). Fatigue in ambulatory patients with advanced lung cancer: prevalence, correlated factors,and screening. Journal of Pain and Symptom Management, 22(1), 554-564. Piper, B. F., Lindsey, A. M., & Dood, M. (1987). Fatigue mechanisms in cancer patients: Developing nursing theroy. Oncology Nursing Forum, 14 (6), 17-23. Pirl, W. F., & Roth, A. J. (1999). Diagnosis and treatment of depression in cancer patients. Oncology, 13, 1293-1301. Ramalingam, S. & Belani, C. P.(2002). Meaningful survival in lung cancer patients. Seminars in Oncology, 29(1 Suppl. 4), 125-131. Respini, D., Jacobsen, P. B., Thors, C., Tralongo, P., & Balducci, L. (2003). The prevalence and correlates of fatigue in older cancer patients. Critical Reviews in Oncology/Hematology, 47(3), 273-279. Roscoe, J. A., Morrow, G. R., Hickok, J. T., et al. (2002). Temporal interrelationships among fatigue,circadian rhythm and depression in breast cancer patients undergoing chemotherapy treatment. Supportive Care in Cancer, 10(4), 329-336. Sarna, L. (1993a). Correlates of symptom distress in women with lung cancer. Cancer Practice, 1(1), 21-28. Sarna, L. (1993b). Women with lung cancer. Impact on quality of life. Quality of Life Research, 2(1), 13-22. Sarna, L. (1998). Effectiveness of structured nursing assessment of symptom distress in advanced lung cancer. Oncology Nursing Forum, 25(6), 1041-1048. Sarna, L., Padilla, G., Holmes, C., Tashkin, D., Brecht, M. L., & Evangelista, L. (2002). Quality of life of long-term survivors of non-small-cell lung cancer. Journal of Clinical Oncology, 20(13), 2920-2929. Savard, J., & Morin, C. M. (2001). Insomnia in the context of cancer: A review of a neglected problem. Journal of Clinical Oncology, 19(3), 895-908. Sheely, L. C. (1996). Sleep disturbances in hospitalized patients with cancer. Sleep, 23 (1), 109-111. Silberfarb, P. M., Hauri, P. J., Oxman, T. E., & Schnurr, P. (1993). Assessment of sleep in patients with lung cancer and breast canver. Journal of Clinical Oncology, 11, 997-1004. Simon, M., Argiris, A., Murren, J. R. (2004). Progress in the therapy of small cell lung cancer. Crit Rev Oncol Hematol, 49(2), 119-133. Smets, E. M., Visser, M. R., Willems-Groot, A. F., et al. (1998). Fatigue and radiotherapy: (A) experience in patients undergoing treatment. British Journal of Cancer, 78 (7), 899-906. Smith, E. L., Hann, D. M., Ahles, T. A., Furstenberg, C. T., Mitchell, T. A., Meyer, L., et al. (2001). Dyspnea, anxiety, body consciousness, and quality of life in patients with lung cancer. Journal of Pain & Symptom Management, 21(4), 323-329. Stone, P. Richards, M., A‘Hern, R., Hardy, J. (2000). A study to investigate the prevalence, severity, and correlates of fatigue among patients with cancer in comparison with a control group of volunteers without cancer. Annals of Oncology, 11(5), 561-567. Tanaka, K., Akechi, T., Okuyama, T., Nishiwaki, Y., & Uchitomi, Y. ( 2002a). Impact of dyspnea, pain, and fatigue on daily life activities in ambulatory patients with advanced lung cancer. Journal of Pain and Symptom Management, 23(5), 417-423. Tanaka, K., Akechi, T., Okuyama, T., Nishiwaki, Y., & Uchitomi, Y. ( 2002b). Factors correlated with dyspnea in advanced lung cancer patients: organic causes and what else?. Journal of Pain and Symptom Management, 23(6), 490-500. Tanaka, K., Akechi, T., Okuyama, T., Nishiwaki, Y., & Uchitomi, Y. ( 2002c). Prevalence and Screening of Dyspnea Interfering with Daily Life Activities in Ambulatory Patients with Advanced Lung Cancer. Journal of Pain and Symptom Management, 23(6), 484-489. Tchekmedyiann, N. S., Kallich, J., McDermott, A. Fayers, P., & Erder, M. H. (2003). The relationship between psychologic distress and cancer-related fatigue. Cancer ,98(1), 198-203. Tsuno, N., Besset, A., & Ritchie, K. (2005). Sleep and depression. Journal of Clinical Psychiatry, 66(10), 1254-69 Uchitomi, Y., Mikami, I., Kugaya, A., et al. (2000). Depression after successful treatment for nonsmall cell lung carcinoma. Cancer, 89, 1172-1179. Uchitomi, Y., Mikami, I., Nagai, K., et al. (2003). Depression and psychological distress in patients during the year after curative resection of non-small-cell lung cancer. Journal of Clinical Oncology, 21(1), 69-77. Voderholzer, U., Hohagen, F., Klein, T., Jungnickel, J., Kirschbaum, C., Berger, M., et al . (2004). Impact of sleep deprivation and subsequent recovery sleep on cortisol in unmedicated depressed patients. American Journal of Psychiatry, 161(8), 1404-1410. Vogelzang, N. J., Breitart, W., Cella, D., et al. (1997). Patient, caregiver, and oncologist perceptions of cancer-related fatigue: results of a tripart assessment survey. Seminars in Hematology , 34(Suppl.), 4-12. Wang, X. S., Giralt, S. A., Mendoza, T. R., Engstrom, M. C., Johnson, B. A., Peterson, N., et al. (2002). Clinical factors associated with cancer-related fatigue in patients being treated for leukemia and non-Hodgkin's lymphoma. Journal of Clinical Oncology, 20 (5) , 1319-1328. Welch, H. G., Schwartz, L. M. & Woloshin, S. (2000). Are increasing 5-year survival rates evidence of success against cancer? Journal of the American Medical Association, 283, 2975-2978. Winnningham, M. L., Nail, L. M., Burke, M. B., et al. (1994). Fatigue and the cancer experience; the state of the knowledge. Oncology Nursing Forum, 21, 23-36. Wolfe, G. (2000). Fatigue: the most important consideration for the patient with cancer. Caring Magazine, 19(4), 46-17. Zigmond, A. & Snaith, R. P. (1983). The Hospital Anxiety and Depression Scale. Acta Psychiatrica Scanainavica, 67, 367-370.
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